Overview of Cellular Measurements
What can be quantified?
1. Basic parameters of the cell population
- Cell number
- Cell proliferation
- Cell death
2. Dynamic parameters of the cell population
- Migration
- Attachment
- Shape, size, rates of change
- Mitotic index
3. Morphological features
- Neurite outgrowth
- Meaurement of vessel length and number of branch points
- Cytoplasmic and nuclear changes due to toxic insult
- Recognition of vacuole formation
4. Morphology with recognition of the cell types
- Co-cultures and heterogeneous cell populations
- Analysis of differentiated cell populations
- Study of nano-particles/nano-tubes
5. Phenotypic cellular assays
- siRNA gene knockdown assay
- cDNA vectors
